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Research Progress on the Correlation between Intrauterine Adhesion and Reproductive Tract Microecology

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DOI: 10.23977/medsc.2025.060418 | Downloads: 1 | Views: 69

Author(s)

Fei Wang 1, Jin Lin 1, Yangjing Long 1, Yan Wang 2, Xu Ding 2, Yanhong Huang 2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Xi'an International Medical Center Hospital, Xi'an, Shaanxi, 710100, China

Corresponding Author

Yanhong Huang

ABSTRACT

Intrauterine adhesions (IUA) is a common complication after gynecological intrauterine surgery. Endometrial fibrosis and inflammatory response are considered the main causes of its occurrence and development. In recent years, an increasing number of research evidences have shown that IUA is closely related to the dysregulation of the reproductive tract microbiota, and the two may interact through pathways such as immune dysregulation, activation of the fibrosis pathway, and inflammatory response. This paper reviews the relevant research results of IUA and the reproductive tract microbiota, in order to provide new treatment ideas for exploring the pathogenesis of IUA and improving IUA from the perspective of adjusting the balance of the flora in the future. 

KEYWORDS

Intrauterine Adhesion, Reproductive Tract Microecology, Uterine Microecology, Vaginal Microecology

CITE THIS PAPER

Fei Wang, Jin Lin, Yangjing Long, Yan Wang, Xu Ding, Yanhong Huang, Research Progress on the Correlation between Intrauterine Adhesion and Reproductive Tract Microecology. MEDS Clinical Medicine (2025) Vol. 6: 119-127. DOI: http://dx.doi.org/10.23977/medsc.2025.060418.

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