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Application of Brain Imaging Technology in the Study of Acupuncture Mechanism and Disease Curative Effect

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DOI: 10.23977/medsc.2025.060302 | Downloads: 9 | Views: 231

Author(s)

Ting Qu 1, Yaxin Jiao 1, Wei Fang 1, Zhiwei Zhang 2, Zhaoxin Wan 3

Affiliation(s)

1 College of Acupuncture and Tuina, Shaanxi University of Chinese Medicine, Xianyang, 712000, Shaanxi, China
2 The First Clinical Medical College, Shaanxi University of Chinese Medicine, Xianyang, 712000, Shaanxi, China
3 Rehabilitation Department, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, 710000, Shaanxi, China

Corresponding Author

Zhaoxin Wan

ABSTRACT

Research back ground: Acupuncture and moxibustion is a treatment method passed down for thousands of years, and it is still considered "unscientific" despite significant clinical efficacy. In the scientific research of acupuncture and moxibustion, how to promote the "modernization of acupuncture and moxibustion" has become a frontier field, combining modern imaging and acupuncture treatment, and further visualization research has become a trend. The literature on" imaging and acupuncture" in 2022 was collected from the database of "China National Knowledge Network", and the endnoteX9.1 software was imported to screen the literature on MRI technology and acupuncture combined with the research perspective. Through the analysis and summary of the literature on acupuncture MRI in the past five years, the changes of image data before, during and after acupuncture treatment of diseases were combined with acupuncture efficacy. This article explores the scientific nature of MRI technology in the visualization of acupuncture mechanism and therapeutic effect. In the acupuncture treatment of dominant diseases such as stroke, pain and mental diseases, MRI technology can confirm the imaging changes of patients before and after treatment, and further clarify the acupuncture mechanism of the central system and peripheral nerves, which is conducive to the application of acupuncture imaging in clinical practice and improve the clinical curative effect of acupuncture.

KEYWORDS

Acupuncture Science; Acupuncture Mechanism; Brain Imaging Technology; Acupuncture Imaging; Clinical Curative Effect of Acupuncture

CITE THIS PAPER

Ting Qu, Yaxin Jiao, Wei Fang, Zhiwei Zhang, Zhaoxin Wan, Application of Brain Imaging Technology in the Study of Acupuncture Mechanism and Disease Curative Effect. MEDS Clinical Medicine (2025) Vol. 6: 7-14. DOI: http://dx.doi.org/10.23977/medsc.2025.060302.

REFERENCES

[1] Xu Jianyang, Wang Xueyong, Zhang Yuan, et al. Imaging of Acupuncture and Moxibustion -- A New Subject in the Study of Acupuncture and Moxibustion Mechanism and Acupoint Compatibility[J]. Shanghai Journal of Acupuncture and Moxibustion, 2005, (01): 31-34.
[2] Wang Xu, Fan Zhengcui, Zhang Zhen, et al. Application of in vivo brain imaging technology in basic research of acupuncture encephalopathy [J]. Chinese Acupuncture and Moxibustion, 2023, 43(12): 1363-1369. 
[3] Gao X Y, Han S, Huang Q, et al. Calcium imaging in population of dorsal root gang lion neurons unravel snovel mechanisms of visceral pain sensitization and refer red somatic hypersensitivity[J]. Pain, 2021, 162(4): 1068-1081.
[4] Chen C, Zhang J H, Sun L L, et al. Long-term imaging of dorsal root Ganglia in awake be having mice[J]. Nat Commun, 2019, 10(1): 3087.
[5] Gong P, Zhang S S, Ren L, et al. Electroacupuncture of the trigeminal nerve causes Nmethyl-D-aspartate receptors to mediate blood-brain barrier opening and induces neuronal excitatory changes[J]. Front Cell Neurosci, 2022, 16: 1020644.
[6] Jiang Y M, Lin Y S, Tan Y H, et al. Electroacupuncture ameliorates cerebrovascular impairment in Alzheimer’s disease mice via melatonin signaling[J]. CNS Neurosci Ther, 2023, 29(3): 917-931.
[7] Cui S, Yao S Q, Wu C X, et al. Electroacupuncture involved in motor cortex and hypoglossal neural control to improve voluntary swallowing of poststroke dysphagia mice[J]. Neural Plast, 2020, 2020: 8857543.
[8] Ding N, Liu X X, Chen N B, et al. Lack of association between acupoint sensitization and microcirulatory structural changes in a mouse model of knee osteoarthritis: a pilot study[J]. J Biophotonics, 2019, 12(6): e201800458.
[9] Kimura K, Ryujin T, Uno M, etal. The effect of electroacupuncture with different frequencies on muscle oxygenation in humans[J]. Evid Based Complement Alternat Med, 2015, 2015: 620785.
[10] Wei Wenjing, Liao Meihua, Tan Yuhang, et al. Study on the Regulatory Effect of Electroacupuncture on Renal Vascular Microcirculation in Diabetic Mice Based on Two-Photon Technology [J]. Acupuncture Research, 2022, 47(06):497-503.
[11] Fang Jiliang. Minutes of the first international fMRI Symposium on acupuncture brain effects [J]. Chinese Journal of Integrated Traditional Chinese and Western medicine imaging, 2012, 10(04): 373.
[12] Rong Peijing, Fang Jiliang, Yu Yutian, et al. Research progress of neural regulation technology based on acupuncture and moxibustion brain science [J]. Science and Technology Guide, 2017, 35(11): 77-84. 
[13] Cai R, Shen G, Wang H, et al. Brain functional connectivity network studies of acupuncture: a systematic review on resting-state fMRI[J]. Journal of Integrative Medicine, 2018, 16(01): 26-33.
[14] Lu F Y, Gao J H, Wang Y Y, et al. Effects of three needling manipulations of the right-side Zusanli(ST36)on brain using functional magnetic resonance imaging[J]. J Tradit Chin Med, 2017, 37(3): 298-307. 
[15] Shi Xuemin. Study on the Correlation between Acupuncture Manipulation and Clinical Effect-The Relationship between Acupuncture Direction, Depth, Surgery and Corresponding Disease at the Same Acupoint [J]. Journal of Traditional Chinese Medicine, 2012, 27(09): 1077-1079.
[16] Hu Jianping, Li yinguan, Cao Dairong, et al. A comparative study on fMRI of different methods of acupuncture at Neiguan point [J]. Modern Chinese doctors, 2008 ,46(33): 4-7+10.
[17] Yu Huijuan. Study on the effect of different stimulation amount on brain activity of Zusanli point by functional magnetic resonance imaging [D]. Shandong University of Traditional Chinese Medicine, 2014.
[18] Han Xiao. Brain effect mechanism of acupuncture intervention on stroke based on whole brain functional network [D]. Beijing University of Chinese Medicine, 2019.
[19] Jiang Lan. Research on Acupuncture Regulation Mechanism of Stroke Hemiplegia Based on Bilateral Brain Connection [D]. Beijing University of Traditional Chinese Medicine, 2020.
[20] Gong Zhigang, Fu Zhihui, Su Zhaofeng, et al. Research on the curative effect of acupuncture on Stroke hemiplegia with wind phlegm and blood stasis syndrome based on functional magnetic resonance imaging [J]. Modern Journal of Integrated Traditional Chinese and Western medicine, 2022,31(23):3269-3274.
[21] Yang Fuxia, Hou Dongmei, Gao Jinyun, et al. Neuroimaging observation of the effect of acupuncture on motor function and corticospinal tract injury after cerebral infarction [J]. Chinese Rehabilitation Theory and Practice, 2021,27(11):1312-1317.
[22] Dong Xiaohui, Zhou Jun, Cheng Shirui, et al. Research Progress and Discussion on Prediction of Therapeutic Effect of Acupuncture on Migraine Based on Neuroimaging [J]. World Science and Technology-Modernization of Traditional Chinese Medicine, 2021, 23(01):197-201.
[23] Niu Juan, Liu alum, Zhou Li, et al. Characteristics and mechanism of emotional representation in patients with depression [J]. Chinese Journal of Clinical Psychology, 2023, 31(04):792-796 + 791.
[24] He Jiakai. Clinical Efficacy and Brain Effect Mechanism of Transcutaneous Cranial-Ear Acupoint Electrical Stimulation of "Tune Chu Qi Shen" [D]. Chinese Academy of Chinese Medical Sciences, 2022.
[25] Chen Ying, Sun Jingqing, Hong Jiahui, et al. Changes in brain function activity of migraine comorbid anxiety and depression and the mechanism of acupuncture on its regulation: a Meta-analysis of fMRI research [J]. Tianjin Traditional Chinese Medicine, 2023, 40(09): 1134-1143.
[26] Yin Tao, Teng Yuk, Zeng Fang. Current Situation and Prospect of Acupuncture Neuroimaging Research [J]. Life Sciences, 2022,34(05):517-524.
[27] Cheng Dongfeng, Li baopeng, Jia Rong-Ze, et al. Research progress of functional brain imaging on brain effects of acupuncture [J]. Journal of Medical Imaging, 2022, 32(06): 1029-1031+1035.

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