High-throughput screening of medical disease biomarkers and the evaluation of their value in early diagnosis
DOI: 10.23977/medbm.2024.020213 | Downloads: 21 | Views: 753
Author(s)
Yuheng Zhang 1, Jiaqi Ren 1, Runxiu Chen 1, Han Wang 1
Affiliation(s)
1 College of Medical, Shihezi University, Shihezi, Xinjiang, China
Corresponding Author
Yuheng ZhangABSTRACT
Internal medicine diseases pose a major threat to global health, and early diagnosis is the key to improving treatment effectiveness. This study used high-throughput screening techniques to successfully identify potential biomarkers associated with the occurrence and development of internal diseases. Early detection of these biomarkers offers new possibilities for disease diagnosis, and their expression levels are closely associated with the disease process. The study also analyzes the advantages and limitations of high-throughput screening technology and proposes corresponding improvement strategies. Despite progress in the screening and evaluation of biomarkers, challenges are needed to improve technical sensitivity, specificity and translation of clinical applications. Future studies are needed to further explore the clinical application potential of these biomarkers and to develop more precise and efficient diagnostic methods.
KEYWORDS
Biomarkers, high-throughput screening, early diagnosis, medical diseasesCITE THIS PAPER
Yuheng Zhang, Jiaqi Ren, Runxiu Chen, Han Wang, High-throughput screening of medical disease biomarkers and the evaluation of their value in early diagnosis. MEDS Basic Medicine (2024) Vol. 2: 90-95. DOI: http://dx.doi.org/10.23977/medbm.2024.020213.
REFERENCES
[1] Yarmey R V, Miguel S A. Biomarkers for aging in Caenorhabditis elegans high throughput screening.[J]. Biochemical Society transactions, 2024
[2] Ren Dandan. Application of a new method for fluorescence sensing based on nanomaterials in biomarker detection [D]. Nanjing Medical University, 2023.
[3] Li Qiong, Zhang Yan. Progress in investigating the role of circulating free nucleic acids as epigenetic markers in precision medicine [J]. Modern Medicine and Health, 2022, 38 (22): 3849-3853 + 3857.
[4] Han Shanying. Cancer biomarkers screening based on extracellular vesicle proteomics techniques [D]. Southeastern University, 2022.
[5] Fu Qiang, Deng Xiaofang, Akindavyi Gael, et al. Study on biomarkers for screening of aortic dissection by high-throughput technology [J]. Journal of Clinical Cardiovascular Diseases, 2021, 37 (10): 952-958.
[6] Wang Hongyang. Tumor biomarker development in the era of precision medicine [J]. Journal of Shandong University (Medical edition), 2018,56 (10): 1-2.
[7] Yu Li. Study on metabolic characteristics and early diagnosis of small cell lung cancer based on new-generation metabolomics techniques [D]. China Medical University, 2018.
[8] A G M, Michelangelo C, Umberto G. Responsible Precision Medicine in Pediatric Acute Respiratory Distress Syndrome: The Challenge of Searching for Biomarker-Driven Earlier Diagnosis, Effective Treatment, and Stratified Outcomes.[J].Critical care medicine, 2018, 46(1):172-174.
[9] Zhu Minhui, Zheng Hongliang. New progress in the early diagnosis of head and neck tumors in the era of precision medicine [J]. Journal of Clinical Otolaryngology, Head and Neck Surgery, 2017, 31 (22): 1770-1774.
Downloads: | 1586 |
---|---|
Visits: | 78183 |
Sponsors, Associates, and Links
-
MEDS Clinical Medicine
-
Journal of Neurobiology and Genetics
-
Medical Imaging and Nuclear Medicine
-
Bacterial Genetics and Ecology
-
Transactions on Cancer
-
Journal of Biophysics and Ecology
-
Journal of Animal Science and Veterinary
-
Academic Journal of Biochemistry and Molecular Biology
-
Transactions on Cell and Developmental Biology
-
Rehabilitation Engineering & Assistive Technology
-
Orthopaedics and Sports Medicine
-
Hematology and Stem Cell
-
Journal of Intelligent Informatics and Biomedical Engineering
-
MEDS Stomatology
-
MEDS Public Health and Preventive Medicine
-
MEDS Chinese Medicine
-
Journal of Enzyme Engineering
-
Advances in Industrial Pharmacy and Pharmaceutical Sciences
-
Bacteriology and Microbiology
-
Advances in Physiology and Pathophysiology
-
Journal of Vision and Ophthalmology
-
Frontiers of Obstetrics and Gynecology
-
Digestive Disease and Diabetes
-
Advances in Immunology and Vaccines
-
Nanomedicine and Drug Delivery
-
Cardiology and Vascular System
-
Pediatrics and Child Health
-
Journal of Reproductive Medicine and Contraception
-
Journal of Respiratory and Lung Disease
-
Journal of Bioinformatics and Biomedicine