Progress in the Treatment of Allergic Diseases with Radix Saposhnikoviae

Zhenhua Zhang; Jingming Zhang

doi:10.23977/medcm.2024.060314

Progress in the Treatment of Allergic Diseases with Radix Saposhnikoviae

Download as PDF

DOI: 10.23977/medcm.2024.060314 | Downloads: 15 | Views: 796

Author(s)

Zhenhua Zhang ¹, Jingming Zhang ^1,2

Affiliation(s)

¹ Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
² Shaanxi Provincial Key Laboratory of TCM Physique and Disease Prevention and Treatment, Xianyang, Shaanxi, 712046, China; Shaanxi Administration of Traditional Chinese Medicine Key Laboratory of Theory of Visceral Manifestation, Xianyang, Shaanxi, 712046, China

Corresponding Author

Jingming Zhang

ABSTRACT

Radix Saposhnikovia is known as "the holy medicine for dispelling wind", and is widely used in the treatment of allergic diseases. Single drug, drug pair and compound prescription of Radix Saposhnikovia can exert antiallergic effects through multiple components, multiple targets and multiple pathways. The main mechanisms are to reduce IgE level, reduce mast cell degranulation and release of histamine, regulate immune and inflammatory factors, and correct Th1/Th2 balance. The research progress and mechanism of single herbal medicine, drug pair and compound prescription of Radix Saposhnikoviae in preventing and treating allergic diseases are summarized in order to provide theoretical support for clinical treatment.

KEYWORDS

Radix Saposhnikoviae; anti-allergy; allergic disease; drug pair; compound prescription

CITE THIS PAPER

Zhenhua Zhang, Jingming Zhang, Progress in the Treatment of Allergic Diseases with Radix Saposhnikoviae. MEDS Chinese Medicine (2024) Vol. 6: 99-105. DOI: http://dx.doi.org/10.23977/medcm.2024.060314.

REFERENCES

[1] Jia Q, Sun W, Zhang L, et al. Screening the anti allelic components in Saposhnikoviae Radiox using high expression Mas correlated G protein coupled receiver X2 cell membrane chromatography online coupled with liquid chromatography and mass spectroscopy [J]. Journal of Separation Science, 2019, 42 (14): 2351-2359
[2] Li XS. Therapeutic effect of Saposhnikoviadivaricata on type I allergy [D]. Hebei University, 2021
[3] Jiang H, Hu L L, Wang Z W, et al. Comparative study on pharmacological activity of ledebouriella chromone monomer by intravenous administration [J]. Lishizhen Medicine and Materia Medica Research, 2016, 27 (7): 1575-1577.
[4] Wang Xiaoyu. Cimifugin reduces the recurrence of allergie inflammationbased on the regulation of microRNAs on epithelial junction proteins [D]. Nanjing University of Traditional Chinese Medicine, 2016
[5] Geng Yumei, Zhang Zhenwei, Shi Lei. Effect of Polysaccharides from Radix Saplshnikoviae on the Immune Factors in Rats with Allergic Rhinitis [J]. China Pharmacist, 2017, 20 (7): 1188-1191.
[6] Ren J, Han Y, Zhang Z X, et al. The effects of polysaccharides from radix sandifoliae japonicae on behavior , AQP5 and nasal mucosa tissues of allergic rhinitis rats based on NFKB/STAT3 signaling pathway [J]. Medical Journal of West China, 2023, 35 (1): 39-45.
[7] Xian ZM, Wang Chongyang, Jiang Jingzhi, et al. Effects of imperatorin on IgE mediated activation of mast cells [J]. Immunological Journal, 2019, 35 (02): 126-131.
[8] Lin CL, Hsiao G, Wang CC, et al. Imperial exercises antagonistic effects in Th2 mediated acute asthma via introduction of IL-10 producing regulatory T cells by modulating the function of dendritic cells [J]. Pharmaceutical Research, 2016, 110:111-121
[9] WANG Dandan. Prescription rules analysis and experimental research oftraditional Chinese medicine treatment ofallergic skin diseases based on data mining [D]. Guangxi University of Traditional Chinese Medicine, 2023
[10] Hou HE X, Liao G L, Li H, et al. Medication Rule and Network Pharmacology Analysis of Traditional Chinese Medicine Compound Patent in the Treatment of Urticaria [J]. Journal of Liaoning University of Traditional Chinese Medicine, 2023, 25 (5): 80-85.
[11] Li Qin. Exploring Professor Xu Aiqin's Medication Rule and Curative EffectMechanism in The Treatment of Urticaria Based on Data Miningand Network Pharmacology [D]. Hubei University of Traditional Chinese Medicine, 2022
[12] Shi J, Zhao H, Min Z S, et al. Study on the Mechanism of Schizonepeta and Saposhnidoviae Campibility in the Treatment of Atopic Dermatitis Based on the Method of Network Pharmacology [J]. Yunnan Journal of Traditional Chinese Medicine and Materia Medica, 2021, 42 (03): 15-21.
[13] Ji Lu. Rearch on the Mechnism of Huangqi-Fangfeng andMahuang-Gancao Regarding to the Effect on Allergic diseases [D]. Nanjing University of Traditional Chinese Medicine, 2017
[14] Liu Ling, Zhao Xiaoli, Di Liuqing, et al. Effect of Astragalus membranaceus on metabolism of Prim-O-glucosylcimifugin and 5-O-methylvisaminoside in Radix Saposhnikoviae by intestinal flora method [J]. Chinese Patent Medicine, 2016, 38 (02): 421-425.
[15] Liao Y, Zhao C B, Song Y J, et al. Mechanism of Wumei-Fangfeng herb pair in treatment of allergic asthma based on network pharmacology [J]. Central South Pharmacy, 2020, 18 (1): 138-143.
[16] Wu Xianbo, Zhu Haiyan, Li Xiang, et al. Anti-allergy mechanism of fangfeng-wumei pair based on expressions of PAR-2 [J]. Journal of Beijing University of Traditional Chinese Medicine, 2015, 38 (10): 682-685.
[17] Wu Xianbo, Tang Songqi, Wang Mingyi, et al. Study on new mechanism and effect of medicine suits as divaricate saposhnikovia root-smoked plum on expression of PAR-2 and blocking mast cell degranulation [J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2016, 31 (03): 1089-1092.
[18] Wu Xianbo, Zhu Haiyan, Li Taifeng, et al. Effect of Fangfeng-Wumei Compatibility to Th2-type Cytokines Produced by Mast Cell and Related Mechanism [J]. Journal of Chengdu University of Traditional Chinese Medicine, 2015, 38 (03): 20-22.
[19] Zhang Weiming. To explore the mechanism of Xinyi Powder in the treatmentof allergic rhinitis based on network pharmacology [D]. Southern Medical University, 2023
[20] Liu JL, Dan WC, He QY, et al. Research on Medication Rules and Mechanism for Treatment of Allergic Rhinitis Based on National Patents TCM Compound [J]. Journal of Liaoning University of Traditional Chinese Medicine, 2020, 22 (8): 134-139.
[21] Li YS, Xie H, Liu Y, et al. Research on the mechanism of saposhnikoviae radix-magnoliae flos herb pairs on the treatment of allergic rhinitis based on network pharmacology [J]. Journal of Chinese Ophthalmology and Otorhinolaryngology, 2020, 10 (4): 185-190.
[22] Wang Yu. Clinical observation of modified Yu-ping-feng Powder combined with Cetirizine syrup in treating allergic cough in Children [D]. Nanjing University of Traditional Chinese Medicine, 2018
[23] Zheng Jie, Bao Kaifan, Li Wei, et al. Effects and Mechanisms of Yupingfeng San on Anti-Allergic Recurrence Based on "Yiqi Gubiao" Efficacy [J]. Journal of Nanjing University of Traditional Chinese Medicine, 2019, 35 (5): 606-612.
[24] Wu Zilu, Li Jingbo, Wang Junjie, et al. Mechanism of Yupingfeng San Against Allergic Rhinitis Through ROS/NLRP3/Caspase-l Signaling Pathway [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2023, 29 (24): 1-10.
[25] Wu Minmin, Huang Shengli. Observation on the efficacy of Fangfengtongsheng Granules combined with Citicoline Loratadine Tablets in the treatment of urticaria [J]. Journal of Dermatology and Venereology, 2019, 41 (5): 721-722.
[26] Wang Yong. Treatment of 80 cases of hormone-resistant atopic dermatitis of the face with additional reduction of Fangfengtongsheng San [J]. Journal of China Prescription Drug, 2018, 16 (4): 95-96.
[27] Chen GF, Hao JX, Gao J, et al. Protective Effect of Fangfeng Tongsheng Pill on Mice with Atopic Dermatitis [J]. Chinese Archives of Traditional Chinese Medicine, 2022, 40 (1): 139- 143, 278 -285.
[28] Wang Yuanfang, Wang Lin, Z Effects of Fangfeng Tongsheng Granule on Chronic Urticaria Model Rats [J]. Chinese Journal of Integrated Traditional and Western Medicine, 2018, 38 (11): 1374-1378.
[29] Pei Yue, Ping Ruiyue, Yang Xianping, et al. Experiences of national medical master Xuan Guowei in the treatment of urticaria using allergy decoction[J]. Sichuan Traditional Chinese Medicine, 2019, 37(04):7-8.
[30] Qin L L, Lan Y Y, Ma S R. Effects of Modified Guomin Decoction on Treg Cell Specific Transcription Factor in Mice with Allergic Asthma [J]. Traditional Chinese Drug Research and Clinical Pharmacology, 2017, 28 (3): 332-335.
[31] Qin L, Huang B X, Lu J, et al. Effects and mechanism of Modified Guomin Decoction on CD4+T cell differentiation in allergic asthmatic mice [J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2022, 37 (6): 3578-3583.

Subscription

E-Mail Alert

Downloads:	8494
Visits:	470882

Progress in the Treatment of Allergic Diseases with Radix Saposhnikoviae

Author(s)

Affiliation(s)

Corresponding Author

ABSTRACT

KEYWORDS

CITE THIS PAPER

REFERENCES

RESOURCES

JOIN US

PUBLICATION SERVICES

CONTACT US