Review of the Research on Animal Models of Heart-Kidney Disharmony in Traditional Chinese Medicine

Guoliang Xiong; Jing Ma

doi:10.23977/medcm.2024.060310

Review of the Research on Animal Models of Heart-Kidney Disharmony in Traditional Chinese Medicine

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DOI: 10.23977/medcm.2024.060310 | Downloads: 15 | Views: 627

Author(s)

Guoliang Xiong ¹, Jing Ma ²

Affiliation(s)

¹ Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
² First Affiliated Hospital of Air Force Military Medical University, Xi'an, Shaanxi, 710032, China

Corresponding Author

Jing Ma

ABSTRACT

As a typical syndrome of Chinese medicine, heart-kidney disharmony may be the cause of a series of diseases. The current established animal models of heart-kidney disharmony include animal models of heart-kidney disharmony insomnia, animal models of heart-kidney comorbidity, and animal models of heart-kidney co-treatment to prove heart-kidney correlation. Most of these animal models have only partially simulated some symptoms, rather than truly reflecting the syndrome of heart-kidney disharmony in Chinese medicine. In future, when further improving the animal model of heart-kidney disharmony, both main and concomitant symptoms of heart-kidney disharmony should be included in the animal model as much as possible, and the method of "determining the syndrome by specific prescriptions" should be used to determine whether the syndrome of the established model is correct.

KEYWORDS

Heart-kidney Disharmony, Heart-kidney Correlation, Syndrome and Symptom, Animal Model, Chinese Medicine

CITE THIS PAPER

Guoliang Xiong, Jing Ma, Review of the Research on Animal Models of Heart-Kidney Disharmony in Traditional Chinese Medicine. MEDS Chinese Medicine (2024) Vol. 6: 66-74. DOI: http://dx.doi.org/10.23977/medcm.2024.060310.

REFERENCES

[1] Li Xiaoyun, Yang Baican. Analysis of the essence of heart-kidney communication[J]. Shanghai Journal of Traditional Chinese Medicine, 2014, 48(09):31-34.
[2] Zhao Weihan, Du Jinxing. Application of the theory of heart-kidney disharmony in modern clinical practice of traditional Chinese medicine[J]. Chinese Journal of Traditional Chinese Medicine, 2012, 27(10):2621-2624.
[3] Gao Yanxia, Han Guixian. A brief analysis of the heart-kidney connection[J]. Shanxi Traditional Chinese Medicine, 1998, 14(5): 7-8, 56.
[4] Guo Jingjing, Song Liqun, Song Yexu. A brief analysis of cardiac changes in chronic kidney disease using the heart-kidney connection theory[J]. Journal of Changchun University of Traditional Chinese Medicine, 2009, 25(01): 5-6.
[5] Ouyang Qiufang, Zhao Hongjia, Guo Quehui, et al. Observation on the effect of Jiaotai Pill on renal function and advanced glycosylation end products in patients with chronic renal-cardiac syndrome (with analysis of 80 cases) [J]. Fujian Medical Journal, 2011, 33(01): 122-124.
[6] Ma Rui. Research on renal damage in cardiovascular disease and the understanding of Chinese and Western medicine [D]. Beijing University of Chinese Medicine, 2008.
[7] Xie Pu. Clinical study on the treatment of primary hypertension in the elderly with Zishen Qingxin Jiangya prescription [D]. Shandong University of Chinese Medicine, 2009.
[8] Hua Yingying. Research on cardiovascular damage in chronic kidney disease and the understanding of Chinese and Western medicine [D]. Beijing University of Chinese Medicine, 2008.
[9] Gao Shuming, Li Peichun, Yang Shuai, et al. On the theory of harmony from the perspective of heart-kidney disharmony. Clinical diagnosis and treatment of pills[J]. Journal of Tianjin University of Traditional Chinese Medicine, 2016, 35(02):73-76.
[10] Mei Yuanting. Clinical observation on the efficacy of Maiwei Dihuang Decoction in the treatment of cardiac neurosis of heart-kidney disharmony type[D]. Heilongjiang University of Traditional Chinese Medicine, 2023.
[11] Wang Jianhui .Theoretical study on the treatment of insomnia from the perspective of heart-kidney disharmony[D]. Heilongjiang University of Traditional Chinese Medicine, 2021.
[12] Wu Xufang, Li Fangjie. Treatment of middle-aged and elderly patients with heart-kidney disharmony Experience with palpitations [J]. Journal of Traditional Chinese Medicine, 2015, 56(05):435-436.
[13] Shi Junbo. Study on the intervention of Jiaotong Xinshen Fang on chronic renal-cardiac syndrome[D]. Ningxia Medical University, 2015.
[14] Wang Yue, Pan Lei, Yang Yang, et al. Treatment of diabetic nephropathy from the perspective of heart-kidney disharmony [J]. ]. Hubei Journal of Traditional Chinese Medicine, 2018, 40(06): 42-44.
[15] Xu Jianfei, Jiao Xiaomin. A brief analysis of Professor Jiao Xiaomin's experience in treating dual heart disease from the perspective of "heart and kidney"[J]. Clinical Research of Traditional Chinese Medicine, 2022, 14(17):118-120.
[16] Luo Linfeng, Huang Min, Jiang Yi, et al. Changes and clinical significance of serum micro-inflammatory factors and N-terminal brain sodium precursor in patients with chronic kidney disease and heart failure[J]. Chinese Journal of Health Journal of Inspection, 2023, 33(12): 1495-1499.
[17] Xu Yan. Study on the central mechanism of Guiganlongmu decoction in treating premature ejaculation of heart-kidney disharmony type based on fMRI technology[D]. Nanjing University of Chinese Medicine, 2022.
[18] Liu Xuebing, Qian Yuzhong, He Ruiying, et al. Treatment of 32 cases of recurrent oral ulcers from the perspective of heart-kidney disharmony[J]. Journal of Changchun University of Traditional Chinese Medicine, 2012, 28(06): 1095-1096.
[19] Li Yue. Clinical efficacy observation of Jiaotai Pill combined with medication in the treatment of patients with generalized anxiety disorder and heart-kidney disharmony[D]. Tianjin University of Traditional Chinese Medicine, 2021.
[20] Zhang Zhiwei, Gao Yuguang. Clinical study on the treatment of anxiety disorder of heart-kidney disharmony type with Huanglian Ejiao decoction[J]. Asia-Pacific Traditional Medicine, 2018, 14(08): 181-183.
[21] Li Hao. Clinical application of Huanglian Ejiao decoction in Treatise on Febrile Diseases Application experience and expansion [C]//Health and Rehabilitation Medicine Professional Committee of Chinese Association of Integrated Traditional Chinese and Western Medicine. Proceedings of the meeting of the Health and Rehabilitation Medicine Professional Committee of Chinese Association of Integrated Traditional Chinese and Western Medicine and the seventh academic seminar. Yuan Hospital;,2011:3.
[22] Yu Chunquan, Li Zhu, Xu Yilan, et al. Clinical observation on the efficacy of Jiaotai Pills combined with fluoxetine hydrochloride in the treatment of depression with heart-kidney disharmony[J]. Tianjin Traditional Chinese Medicine, 2020, 37(03): 291-295.
[23] Quan Shijian, Lin Xinge, Liu Ni. Study on the syndrome properties of PCPA rat insomnia model[J]. Journal of Traditional Chinese Medicine, 2006, (03): 450-451.
[24] Gao Hongli, Tu Xing, Lu Ying, et al. Rat model of insomnia caused by heart-kidney disharmony[J]. Chinese Traditional Patent Medicine, 2014, 36(06):1138-1141.
[25] Qian Lili. Effect of Jiaotai Pill on hypothalamic orexin in rats with rapid eye movement sleep deprivation A[D]. Guangzhou University of Chinese Medicine, 2013.
[26] Lin Wenqiu. Using the heart-kidney correlation theory to explore the intervention of Sanqi oral liquid on renal and heart diseases in rats[D]. Guangzhou University of Chinese Medicine, 2015.
[27] Chen Jiewen , Luo Rongjing, Hu Weian, et al. Experimental study on the theory of "heart-kidney correlation" in traditional Chinese medicine [J]. Journal of Guangzhou University of Traditional Chinese Medicine, 1991, (Z1): 113-118.
[28] Gao Hongshan, Song Kun, Gao Huanping. Experimental study on Zhenwu capsule combined with benazepril in the treatment of dilated cardiomyopathy[J] .Zhejiang Journal of Integrated Traditional Chinese and Western Medicine, 2016, 26(07): 615-617+594.
[29] Feng Zhou, Qu Huiyan, Rong Jingfeng, et al. Effect of Xinshen Tongzhi Decoction on cardiac function in rats with heart failure [J]. Journal of Traditional Chinese Medicine, 2015, 30(05): 690-692.
[30] Kong Fanda, Zhang Yan, Zhu Aisong, et al. Observation of the effect of kidney-tonifying and blood-activating Chinese medicine on osteopontin in rats with chronic heart failure based on the theory of "kidney stores essence and activates blood"[J]. Chinese Journal of Traditional Chinese Medicine, 2018, 33(12):5373-5376.
[31] Yang Jiezhong. Experimental study on the prevention and treatment of femoral head ischemic necrosis based on the theory of heart-kidney interaction[D]. Hubei University of Traditional Chinese Medicine, 2011.
[32] Mao Xinjing. Exploring the cardioprotective effect of Qianyang Yuyin prescription on rats with hypertensive renal injury based on the theory of "heart-kidney correlation"[D]. Nanjing University of Chinese Medicine, 2020.
[33] Zhu Bixiu, Tian Zhejing, Liu Lanying, et al. Study on the effect of nephritis anti-aging solution on improving the renal and cardiac pathology of diabetic nephropathy rats based on the "heart-kidney correlation"[J]. Journal of Hebei Traditional Chinese Medicine, 2020, 35(05): 6-10.
[34] Zhao Shuying, Zhang Chunxiao, Zhang Lei, et al. Experimental study on the mechanism of kidney-tonifying method in the intervention of large artery sclerosis in SHR rats[J]. Journal of Shandong University of Traditional Chinese Medicine, 2018, 42(03): 259-263.
[35] Lin Ye. Research on the construction of animal model of rheumatoid arthritis wind-cold-dampness syndrome based on prescription diagnosis [D]. Hunan University of Traditional Chinese Medicine, 2019.
[36] Yang Meng, Hu Siyuan, Li Lin, et al. Exploring the TCM syndrome types and syndrome essence of isoproterenol-induced chronic heart failure mouse model based on "diagnosis by prescription"[J]. Chinese Pharmacology and Clinical Medicine, 2024, 40(02):101-108.

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Review of the Research on Animal Models of Heart-Kidney Disharmony in Traditional Chinese Medicine

Author(s)

Affiliation(s)

Corresponding Author

ABSTRACT

KEYWORDS

CITE THIS PAPER

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