Education, Science, Technology, Innovation and Life
Open Access
Sign In

Progress in studying polyunsaturated fatty acids in osteoporosis

Download as PDF

DOI: 10.23977/medbm.2024.020208 | Downloads: 19 | Views: 812

Author(s)

Ligang Shan 1, Suriyakala Perumal Chandran 1

Affiliation(s)

1 Faculty of Medicine, Lincoln University College, Petaling Jaya-47301, Malaysia

Corresponding Author

Suriyakala Perumal Chandran

ABSTRACT

Osteoporosis is a metabolic habit disease of the elderly with a high incidence in clinical practice. Age, gender, genetic, endocrine, nutrition, drugs and other factors are the important causes of osteoporosis, but its specific pathogenesis is not clear. In recent years, reports regarding the role of polyunsaturated fatty acids in osteoporosis have gradually increased. There is a correlation between osteoporosis and blood lipid disorders, and polyunsaturated fatty acids play a certain role in the occurrence and development of osteoporosis. Based on this, this paper primarily focuses on the research progress of polyunsaturated fatty acids in relation to osteoporosis.

KEYWORDS

Polyunsaturated fatty acids; osteoporosis; research progress

CITE THIS PAPER

Ligang Shan, Suriyakala Perumal Chandran, Progress in studying polyunsaturated fatty acids in osteoporosis. MEDS Basic Medicine (2024) Vol. 2: 44-48. DOI: http://dx.doi.org/10.23977/medbm.2024.020208.

REFERENCES

[1] Wang Qing, Chen Guomin, Chen Junsheng, et al. Effects of ω -3 polyunsaturated fatty acids on inflammatory response and immune function after lower extremity fracture in the elderly [J]. Journal of Practical Medicine, 2020, 37 (08): 687-689.
[2] Liu Wenqing, Li Yan, Chen Junsheng, et al. Effect of ω -3 polyunsaturated fatty acids on immune response after femoral fracture in the elderly [J]. Chinese Journal of Orthopaedic Surgery, 2019, 27 (22): 2059-2062.
[3] Fu Meng, Zhang Lei, Li Xuejing, et al. Comparative study of fatty acid synthesis in osteoporosis mice by fish oil and safflower seed oil [J]. Marine Medicine of China, 2020, 39 (02): 50-58.
[4] Galea L G ,Sunters A ,Meakin B L,et al. Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4 [J].FEBS Letters, 2011, 585(15):2450-2454.
[5] Wang Yu, Luo Meiyan, Huang Xin, et al. Effect of puerarin plus atorvastatin on COX-2 / PGE 2 / cAMP signaling in hormonal avascular necrosis of the femoral head [J]. Chinese Journal of Bone and Joint, 2019, 8 (05): 392-397.
[6] Nathalie A ,Priyanka K ,Soohyun K,et al Mitochondrial B-oxidation of adipose-derived fatty acids by osteoblast fuels parathyroid hormone-induced bone formation.[J].JCI insight, 2023,8(6):129-136.
[7] hristina W,Toby C,Nikki D, et al.Bone Mineral Density Corrected for Size in Childhood Leukaemia Survivors Treated with Haematopoietic Stem Cell Transplantation and Total Body Irradiation.[J].Hormone research in paediatrics,2018,89(4):246-254.
[8] Chen Zehua, Hu Huiyun, Chen Ying, et al. Progress in the mechanism of ω -3 polyunsaturated fatty acids [J]. Medical Herald, 2018, 37 (11): 1334-1338.
[9] Wang Sizhu, Tang Guangyu. Advances in the analytical techniques of bone marrow fat and its relationship with osteoporosis [J]. Chinese Journal of Osteoporosis, 2022, 28 (04): 601-606.
[10] Luo Na, Sun Zhihong. Progress in studying the mechanism of Omega-3 PUFA in hyperlipidemia [J]. Chinese Oil, 2020, 45 (07): 97-101.
[11] Fang Xiang, Zhou Zhengxin, Zhu Lei, et al. Effect and mechanism of granule intervention in a mouse model of hormonal necrosis of the femoral head [J]. China Tissue Engineering Research, 2024,28 (16): 2599-2604.
[12] Kumar S R, Golden Earth. Experimental study on N-3 polyunsaturated fatty acids promoting bone regeneration in mice (English) [J]. Journal of Molecular Imaging, 2018,41 (03): 287-290.
[13] Deng Xiang-yuan, Zhang Ruiliang, Chen Shuai, et al. N-3 PUFA improves exhaustion in exhaustion exercise mice by inhibiting NLRP 3 inflammasome activity in skeletal muscle [J]. Journal of the Army Military Medical University, 2023, 45 (24): 2521-2529.
[14] Bai Xiaolin, Bo Yuying, Ding Ning, et al. Effect of Antarctic krill oil, fish oil and arachidonic acid oil on lipid metabolism in osteoporosis mice [J]. Food Science, 2022,43 (17): 131-137.
[15] Wang Kai, Zhu Yujie, Li Yuanyuan, et al. Ameliorating effect of ethyl ester type fish oil on OA in mice [J]. Food Science, 2019,40 (05): 143-148.
[16] Liu Qiqi, Liu Min, Yang Jian, et al. LPS stimulates the expression of interleukin 6 and nuclear factor κ B receptor activation factor ligand in mouse MLO-Y4 osteocytes [J]. China Tissue Engineering Research, 2022, 26(20): 3121-3126.
[17] Huang Zexiao, Yang Mei, Lin Shiwei, et al. Correlation between serum n-3 polyunsaturated fatty acid levels and quadriceps muscle strength changes in the early stages of total knee replacement [J]. China Tissue Engineering Research, 2021, 25 (09): 1375-1380.
[18] Ning Weihong, Xu Guozhu, Wang Jianwei. Effect of desoumab on bone mineral density around the proximal femoral component after total hip replacement for postmenopausal osteoporotic femoral neck fracture [J]. Chinese Bone Injury, 2023,36 (11): 1041-1045.
[19] Wen Long. Effect of comprehensive therapy on hip function and bone metabolism after femoral neck fracture with osteoporosis [J]. Practical Journal of Traditional Chinese Medicine, 2023,39 (05): 905-908.
[20] Dai Jiale, Sun Huiping, Hu Jieyun, et al. Effects of osteoporosis on bone metabolism and serum adiponectin in postmenopausal women treated with alendronate and salmon calcium-lowering injection [J]. Guangdong Medicine, 2018, 39 (17): 2663-2666.
[21] Ma Xiaoyong, Gao Fei, Wan Yinghui, et al. Comparison of the clinical treatment effects of elderly postmenopausal osteoporosis [J]. Hebei Pharma, 2019, 41 (23): 3602-3605.
[22] Liang Qiongxian, Zhang Haihong, Liang Jintao, et al. Effect of fish oil on inflammation and bone mineral levels in maintenance hemodialysis patients [J]. Journal of Guangdong Medical University, 2019, 37 (02): 127-131.

Downloads: 1586
Visits: 78168

Sponsors, Associates, and Links


All published work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2016 - 2031 Clausius Scientific Press Inc. All Rights Reserved.