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  4. Vol 6, Issue 2, 2024

Research progress on hot flashes and insomnia in perimenopausal women

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DOI: 10.23977/medcm.2024.060219 | Downloads: 25 | Views: 837

Author(s)

Siqi Mu 1, Min Ma 1, Maoxing Ran 1, Zirui Li 1, Chang Li 1, Qing An 1, Huimin Dang 2, Yanqiao Liu 2

Affiliation(s)

1 The First Clinical Medical College, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China

Corresponding Author

Huimin Dang

ABSTRACT

Insomnia caused by hot flushes can seriously affect the normal life and work of perimenopausal women, and it is easy to cause a variety of complications. How to prevent and treat insomnia related to hot flushes has become the focus of medical researchers. This paper combs the ancient medical books on the etiology, pathogenesis and treatment of insomnia caused by hot flushes in women during perimenopause, and summarizes the difference between deficiency and excess in the disease nature. In the pathogenesis, deficiency is often due to the deficiency of yin and blood, the Yin does not converge the Yang, and the Yang heat disturbs, so the Yang floats and moves and sleeps restlessly. Excess syndrome often turns into heat due to blood stasis, dry excrement and dampness, which disturbs the sleep and makes it difficult to sleep at night. In terms of treatment, according to different pathogenesis, methods such as nourishing yin and reducing fire, nourishing blood and clearing heat, regulating Ying and Wei, activating blood circulation and removing blood stasis, dredging the bowels and discharging heat, clearing heat and dampness, and calming the nerves and calming the mind are adopted.

KEYWORDS

Perimenopausal insomnia, hot flushes, etiology and pathogenesis; Syndrome differentiation and treatment

CITE THIS PAPER

Siqi Mu, Min Ma, Maoxing Ran, Zirui Li, Chang Li, Qing An, Huimin Dang, Yanqiao Liu, Research progress on hot flashes and insomnia in perimenopausal women. MEDS Chinese Medicine (2024) Vol. 6: 151-157. DOI: http://dx.doi.org/10.23977/medcm.2024.060219.

REFERENCES

[1] Samuel L, Antonio C, et al. Fezolinetant for treatment of moderate-to-severe vasomotor symptoms associated with menopause (SKYLIGHT 1): a phase 3 randomised controlled study. [J]. Lancet (London, England), 2023, 401(10382): 1091-1102.
[2] Li Huihao, Wang Jieqiong, Gao Mingzhou et al. Progress in Traditional Chinese Medicine Research on Perimenopausal Heat Disorder [J]. Chinese Journal of Basic Traditional Chinese Medicine, 2019, 25 (03): 413-416. 
[3] Zheng Yanwei, Tao Minfang. Research progress on sleep disorders in perimenopausal women [J]. Journal of Shanghai Jiao Tong University (Medical Edition), 2016, 36 (07): 1088-1092. 
[4] C , R T, E H V A, A C D, et al. Menopausal Vasomotor Symptoms and Risk of Incident Cardiovascular Disease Events in SWAN. [J]. Journal of the American Heart Association, 2021, 10(3). 
[5] Crandall CJ, Tseng CH, Crawford SL, et al. Association of menopausal vasomotor symptoms with increased bone turnover during the menopausal transition. [J]Bone Miner Res 2011; 26: 840.
[6] K J P .Neurokinin 3 receptor antagonists for menopausal vasomotor symptoms.[J].Lancet (London, England), 2023, 401(10382):1055-1058.
[7] Zhang Nianshun. Diagnosis and treatment of hot flashes based on timing [J]. Chinese Community Physician, 1991 (01): 23-24.
[8] Xu Xinyan, Li Jun, Bao Xiaoxia, et al. Professor Guo Weiqin's Experience in Treating Menopausal Insomnia [J]. Grassroots Traditional Chinese Medicine, 2023, 2 (03): 6-9. 
[9] Deng Ying. Zishen Tang for the treatment of 50 cases of menopausal hot flashes and sweating [J]. Shaanxi Traditional Chinese Medicine, 2004 (05): 406-407. 
[10] Mi Xiujuan, Fang Junnan, Yu Xinyuan, et al. Clinical efficacy of Zishui Bugan Tang in the treatment of insomnia caused by liver and kidney deficiency during perimenopause [J]. Chinese Journal of Experimental Formulas, 2022, 28 (16): 116-122.
[11] Zhang Zhongyang, Ling Jiayan, Zhou Dun. Study on the clinical efficacy of modified Huanglian ass hide glue Decoction in treating insomnia of yin deficiency and fire hyperactivity syndrome and its effect on 5-hydroxytryptamine and dopamine levels [J]. Chinese Journal of Traditional Chinese Medicine, 2021, 39 (04): 167-171. 
[12] Wei Xiangling, Sun Haijun. Modified Guipi Tang for the treatment of 47 cases of refractory insomnia [J]. Chinese Journal of Basic Medicine of Traditional Chinese Medicine, 2007 (09): 714. 
[13] Cui Zhenbo, Yang Taiyin. Modified Guizhi Tang for the treatment of 40 cases of menopausal fever [J]. Anhui Journal of Clinical Chinese Medicine, 2003, 15 (6): 478
[14] Liu Yaling, Wang Jiawei. Wang Jiawei's Experience in Treating Perimenopausal Syndrome [J]. Journal of Traditional Chinese Medicine, 2011, 52 (6): 524-525. 
[15] Gao Zhili, He Juan. On Blood Stasis and Insomnia [J]. Tianjin Traditional Chinese Medicine, 2019, 36 (04): 371-373. 
[16] Fu Shuping, Zhang Ronghua, Cai Yu, et al. Treatment of menopausal syndrome based on kidney deficiency and blood stasis [J]. Shaanxi Traditional Chinese Medicine, 2005, 26 (5): 435-436. 
[17] Bu Huanyu. Analysis of Severe Heat in the Afternoon [J]. Journal of Nanjing University of Traditional Chinese Medicine, 2019, 35 (02): 127-129.
[18] Liu Tianping, Wu Jianguang. Experience of Chinese medicine master Wu Bingcai in treating perimenopausal hot flashes and sweating [J]. Journal of Jiangxi University of Traditional Chinese Medicine, 2023, 35 (04): 16-18+22. 
[19] Li Hui, Jiang Qunqun. Clinical experience of Professor Liu Ruifen in treating perimenopausal hot sweating [J]. Journal of Zhejiang University of Traditional Chinese Medicine, 2013, 37 (07): 873-874. 
[20] Zhong Guanghua. Modified Zishui Qinggan Yin for the treatment of 108 cases of perimenopausal hot flashes [J]. Shaanxi Traditional Chinese Medicine, 2004 (11): 977.
[21] Luo Chunhua, Yang Haiyu. Three medical cases of treating insomnia with the combination of Zhizi Black Bean Soup and Guipi Tang. [J]. New Traditional Chinese Medicine, 2020, 52 (13): 204-206 .
[22] Huang Yanmei, Liu Yaqian, Zhou Ying. Study on the therapeutic effect of modified Erxian Heguizhi Tang on menopausal syndrome hot flashes and its impact on gut microbiota structure [J]. New Chinese Medicine and Clinical Pharmacology, 2022, 33 (07): 970-976. 
[23] Li Boyu, Gao Baoyin. Clinical observation of 50 cases of stubborn insomnia with blood stasis type treated with integrated traditional Chinese and Western medicine [J]. Clinical Research of Traditional Chinese Medicine, 2020, 12 (28): 108-110.
[24] Yao Haiqiang, Cui Hongsheng, Guo Gang et al. Wang Qi's use of Xuefu Zhuyu Tang for treatment [J]. Journal of Traditional Chinese Medicine, 2016, 57 (05): 375-378. 
[25] Qi Cuiping. Observation on the therapeutic effect of promoting blood circulation and removing stasis method on menopausal syndrome [J]. Heilongjiang Traditional Chinese Medicine, 2002, (04): 17-18. 
[26] Chen Yifei, Sun Meiling. Analysis and treatment of afternoon hot flashes based on syndrome differentiation [J]. Shi Zhen, Traditional Chinese Medicine, 2021, 32 (03): 689-690.
[27] Jin Zhongyu, Zhang Guifang. 63 cases of menopausal syndrome treated by gallbladder differentiation [J]. Zhejiang Journal of Traditional Chinese Medicine, 2003, (04): 19.

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