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  4. Vol 4, Issue 2, 2024

Effect of Tetrandrine Combined with Bronchoalveolar Lavage on the Clinical Symptom Relief of Pneumoconiosis

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DOI: 10.23977/phpm.2024.040209 | Downloads: 0 | Views: 44

Author(s)

Guangbo Zhang 1

Affiliation(s)

1 Occupational Diseases Hospital of Shandong First Medical University, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong Provinces, China

Corresponding Author

Guangbo Zhang

ABSTRACT

As an occupational disease caused by long-term exposure to dust, pneumoconiosis has seriously affected the health of millions of workers worldwide, especially in the fields of mining, construction, and heavy industry. Due to the difficulty in fundamentally reversing pulmonary fibrosis with early treatment methods and often accompanied by significant side effects, the treatment of pneumoconiosis has always faced enormous challenges. To improve the clinical symptoms and quality of life of patients with pneumoconiosis, this study investigated the effect of tetrandrine combined with bronchoalveolar lavage in the treatment of pneumoconiosis. These patients were randomly divided into two groups. The treatment group received a combination of tetrandrine and bronchoalveolar lavage, while the control group received placebo and conventional supportive treatment. The treatment period is three months, and the patient's clinical symptoms (such as difficulty breathing, cough, and sputum) and changes in lung function test indicators (such as vital capacity and forced expiratory volume in one second) are evaluated. All data is collected and analyzed by professional medical personnel before and after treatment. FEV1 (Forced Expiratory Volume in the first second) data shows that the majority of patients have FEV1 values between 1.8 and 2.5 liters, which means that after one month of treatment,  their lung function has recovered, but the degree of recovery varies. Therefore, the combination of tetrandrine and bronchoalveolar lavage is a safe and effective new therapy for the treatment of pneumoconiosis. This study can provide new ideas for the prevention and treatment of pneumoconiosis, and provide a theoretical basis for further optimizing pneumoconiosis prevention and control strategies. The comprehensive use of this therapy is expected to greatly improve the quality of life of pneumoconiosis patients.

KEYWORDS

Tetrandrine, Bronchoalveolar Lavage, Treatment of Pneumoconiosis, Clinical Symptoms

CITE THIS PAPER

Guangbo Zhang, Effect of Tetrandrine Combined with Bronchoalveolar Lavage on the Clinical Symptom Relief of Pneumoconiosis. MEDS Public Health and Preventive Medicine (2024) Vol. 4: 63-71. DOI: http://dx.doi.org/10.23977/phpm.2024.040209.

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